The invention relates to the identification of a highly stable single domain antibody scaffold (hs2d Ab) and its use in generating synthetic single domain antibody library (hs2d Ab-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.
申请公布号
EP3066120(A1)
申请公布日期
2016.09.14
申请号
EP20140798742
申请日期
2014.11.04
申请人
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);INSTITUT CURIE;UNIVERSITÉ PAUL SABATIER TOULOUSE III;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -
