发明名称 トレハロース及びデキストラン含有哺乳動物細胞移植用溶液
摘要 The problem of the present invention is to provide a method for preserving mammalian cells over a long period of time using a solution for cell transplantation, capable of effectively suppressing cell death when the mammalian cells have been preserved, and the solution for cell transplantation. The present invention is characterized in that mammalian cells are preserved in a physiological aqueous solution for cell transplantation, comprising 2.0 to 6.0% (w/v) of trehalose, a derivative thereof, or a salt of trehalose or the derivative (a trehalose) and 4.0 to 7.0% (w/v) of dextran, a derivative thereof, or a salt of dextran or the derivative (a dextran). The effects of a trehalose and a dextran contained in the physiological aqueous solution for cell transplantation can suppress a decrease in the cell survival rate when mammalian cells are preserved for a long period of time (at least 14 days). The physiological aqueous solution is preferably one selected from the group consisting of lactate Ringer's solution, saline, Ringer's solution, and acetate Ringer's solution; particularly preferred is lactate Ringer's solution or saline.
申请公布号 JP5998265(B2) 申请公布日期 2016.09.28
申请号 JP20150197577 申请日期 2015.10.05
申请人 株式会社大塚製薬工場 发明人 西村 益浩;和田 圭樹;白川 智景;土居 雅子
分类号 C12N5/02;C12N5/0775;C12N5/0783 主分类号 C12N5/02
代理机构 代理人
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