AGENT FOR INHIBITING ODOR OF PYRAZINE DERIVATIVES

摘要

Provided is an agent for reducing odors of pyrazine derivatives based on an olfactory receptor antagonism. The agent for reducing odors of pyrazine derivatives includes at least one antagonist of olfactory receptor OR5K1 as an active ingredient.

主权项

1. A method of reducing an odor of a pyrazine derivative having the formula (I), wherein R1 represents methyl, ethyl, or acetyl; and R2, R3 and R4 each independently represent hydrogen or methyl, wherein the method comprises causing an odor of a pyrazine derivative to exist in the presence of at least one compound selected from the group consisting of the following compounds: 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol; 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethyl-naphthalene; and 4-methyl-3-decen-5-ol;wherein said compound antagonizes the response of olfactory receptor OR5K1 to the pyrazine derivative.