主权项 |
1. A method for monitoring the onset and/or progression of COPD in a subject, the method comprising:
(a) performing FTIR or VFIR spectral analysis of a sputum sample obtained from the subject; and (b) comparing the spectrum produced from the sample with an FTIR or VFIR spectrum from a normal control or for a spectrum previously taken for the subject, wherein a difference between the spectrum produced from the sample and the normal control or spectrum previously taken at one or more wavenumbers within one or more ranges selected from about 940 cm−1 to about 970 cm−1, about 1080 cm−1 to about 1130 cm−1, about 1230 cm−1 to about 1250 cm−1, about 1570 cm−1, about 1590 cm−1, about 1620 cm−1 to about 1650 cm−1, and about 1720 cm−1 to about 1750 cm−1 is indicative of a subject suffering from COPD or the progression of COPD in a subject. |