摘要 |
The invention relates to a biocatalytic process for the oxidation of substituted polycyclic aromatic compounds to the corresponding carboxylic acids and related compounds. In a preferred embodiment the invention describes a method to produce 6-methyl-2-hydroxymethylnaphthalene, 6-methyl-2-naphthoic acid, 2,6-bis(hydroxymethyl)naphthalene and 2,6-naphthalenedicarboxylic acid from 2,6-dimethylnaphthalene. These compounds have been prepared by oxidizing 2,6-dimethylnaphthalene with a single recombinant microorganism containing the enzyme xylene monooxygenase. |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY;BRAMUCCI, MICHAEL, G.;NAGARAJAN, VASANTHA;THOMAS, STUART, M. |
发明人 |
BRAMUCCI, MICHAEL, G.;NAGARAJAN, VASANTHA;THOMAS, STUART, M. |