THREE HYBRID SCREENING ASSAY USING REVERSE TRANSFECTED MAMMALIAN CELL ARRAYS

摘要

Assay methods are provided for performing a three-hybrid assay in mammalian cells. Arrays for conducting the assay methods are also provided. The assays methods and arrays may be used to screen a DNA library to identify the target protein of a known small molecule, study target protein: small molecule interaction, or screen a library of small molecules against a known target protein.