| 发明名称 |
Modified surfaces as solid supports for nucleic acid purification |
| 摘要 |
The invention relates to methods of separating polynucleotides, such as DNA, RNA and PNA, from solutions containing polynucleotides by reversibly binding the polynucleotides to a solid surface, such as a magnetic microparticle. |
| 申请公布号 |
US9464315(B2) |
申请公布日期 |
2016.10.11 |
| 申请号 |
US201313850275 |
申请日期 |
2013.03.25 |
| 申请人 |
Applied Biosystems, LLC |
发明人 |
Latham Gary;Fang Xingwang;Conrad Richard;Kemppainen Jon;Setterquist Robert;Pasloske Brittan |
| 分类号 |
C12Q1/68;C12N15/10 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
Foiles Peter G. |
| 主权项 |
1. A kit comprising a binding buffer and at least one polymer-modified surface, wherein the binding buffer comprises a guanidinium salt and an organic solvent at concentrations for binding polynucleotides to the surface of the polymer-modified surface during use, wherein the polymer-modified surface is further defined as comprising a dextran. |
| 地址 |
Carlsbad CA US |
