发明名称 |
PARA-XYLENE FILMS AND THERAPEUTIC USES THEREOF |
摘要 |
The present invention provides single sheet and compound para-xylene films for therapeutic uses. For example, the present invention provides single sheet para-xylene films useful as tissue separators and/or adhesion barriers in a subject, where the top and/or bottom surfaces of such films have a water contact angle between 75 and 95 degrees (e.g., to prevent adhesion formation). The present invention also provides compound films composed of at least two para-xylene polymer films with a therapeutic molecule layer in between. Such compound films, when used in vivo (e.g., as a tissue separator and to treat inflammation or atrial fibrillation) allow either therapeutic molecule elution through one of the para-xylene layers, or therapeutic molecule release when the compound film is pierced, such as when it is sutured in place. |
申请公布号 |
EP2999427(A4) |
申请公布日期 |
2016.11.16 |
申请号 |
EP20140800460 |
申请日期 |
2014.05.21 |
申请人 |
NORTHWESTERN UNIVERSITY;UNIVERSITY OF MARYLAND, BALTIMORE;ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO |
发明人 |
KAUSHAL, SUNJAY;HO, DEAN;ROBINSON, ERIK M.;MCCARTHY, PATRICK M. |
分类号 |
A61F2/00;A61L31/06 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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