HYALURONIC ACID/METHOTREXATE COMPOUND,申请号EP20050727780-传众专利搜索

发明名称	HYALURONIC ACID/METHOTREXATE COMPOUND
摘要	<p>An object of the present invention is to provide a hyaluronic acid-methotrexate conjugate useful as a therapeutic drug for joint disorders. There is provided a hyaluronic acid-methotrexate conjugate useful for the treatment of joint disorders, wherein methotrexate is conjugated with a hydroxy group of hyaluronic acid through a linker containing a peptide chain consisting of 1 to 8 amino acids, and the linker is conjugated with the hyaluronic acid through a carbamate group.</p>
申请公布号	EP1739097(A1)	申请公布日期	2007.01.03
申请号	EP20050727780	申请日期	2005.04.01
申请人	DENKI KAGAKU KOGYO KABUSHIKI KAISHA;CHUGAI SEIYAKU KABUSHIKI KAISHA	发明人	IKEYA, HITOSHI;MORIKAWA, TADASHI;TAKAHASHI, KOICHI;IZUTANI, NORIYUKI;TAMURA, TATSUYA;OKAMACHI, AKIRA;ISHIZAWA, TAKENORI;SATO, HARUHIKO;HIGUCHI, YOSHINOBU;KATO, TATSUYA;HONMA, AKIE
分类号	A61K47/48;A61K31/519;A61P19/02;C07D475/08;C07D475/10;C07K5/00;C08B37/08	主分类号	A61K47/48
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