The invention relates to compounds, in particular polypeptides that specifically bind to the non-classical MHC protein CD1d and modulate CD1d-mediated biological functions. The invention in particular relates to such compounds and polypeptides comprising or consisting of at least one single domain antibody, and wherein at least one single domain antibody specifically binds to CD1d. Also provided is for methods and use employing such compounds, polypeptides and/or single-domain antibodies.
申请公布号
WO2016122320(A1)
申请公布日期
2016.08.04
申请号
WO2016NL50064
申请日期
2016.01.27
申请人
STICHTING VU-VUMC;STICHTING VUMC
发明人
VAN DER VLIET, JOHANNES JELLE;DE GRUIJL, TANJA DENISE;VERHEUL, HENDRIK MARINUS WILLEM;DE BRUIN, RENÉE CORNELIA GERARDA;LAMERIS, ROLAND