Formulations and methods for treating oral inflammation, injury, or pain

摘要

The present invention generally relates to formulations and methods for treating oral inflammation, oral injury and/or oral pain by applying hydrogel, viscous liquid, or other formulation to the oral cavity. Wet formulations comprise a hydrophilic polymer selected from the group consisting of pyrrolidones, hyaluronic acid and salts thereof, alginic acid and salts thereof, and carrageenans and salts thereof; calcium salts or ions, phosphate salts or ions, and water as well as other optional components. Dry formulations such as powders are also contemplated.

主权项

1. A dry formulation adapted for reconstituting with water to form a liquid formulation for treating oral injury, oral inflammation and/or oral pain, the dry formulation comprising:
one or more hydrophilic polymers, at least one of which is selected from the group consisting of:
pyrrolidones,hyaluronic acids and salts thereof;alginic acids and salts thereof;carrageenans and salts thereof;celluloses;dextrins;and mixtures thereof, wherein said hydrophilic polymers are present in an amount between 4% to 85%, based on the total weight of the dry formulation; from 2.5% to 7% by weight, based on the total weight of the dry formulation, of one or more calcium salts; from 0.4% to 1.2% by weight, based on the total weight of the dry formulation, of one or more phosphate salts; and sodium chloride.