发明名称 |
AQUEOUS SUSPENSION PREPARATION COMPRISING NANOPARTICLES OF MACROLIDE ANTIBACTERIAL AGENT |
摘要 |
[Problem] The purpose of the present invention is to provide an aqueous suspension preparation that comprises a macrolide antibacterial agent as an active component. Specifically, the purpose of the present invention is to provide a pharmaceutical composition that comprises a macrolide antibacterial agent as an active component and that can be put to practical use. [Solution] The present invention provides: an aqueous suspension preparation that is characterized by comprising nanoparticles of a macrolide antibacterial agent and a dispersion stabilizer; an aqueous suspension in which the average particle size of nanoparticles is 500 nm or less and the D90 particle size is 1,500 nm or less; a parenterally administered pharmaceutical composition that comprises this aqueous suspension preparation; an injection preparation; and eye drops or ear drops, more specifically, eye drops for the treatment or prevention of inflammatory diseases of the eye or ear drops for the treatment or prevention of inflammatory diseases of the ear. |
申请公布号 |
EP3067045(A1) |
申请公布日期 |
2016.09.14 |
申请号 |
EP20140860926 |
申请日期 |
2014.11.07 |
申请人 |
ACTIVUS PHARMA CO., LTD. |
发明人 |
TADA, TAKAHIRO;KAGAMI, KAZUHIRO;YOKOTA, SHIRO;KIKUCHI, KENTA |
分类号 |
A61K31/7048;A61K9/10;A61K9/14;A61K31/7052;A61K47/10;A61K47/26;A61K47/32;A61K47/38;A61P29/00;A61P31/04 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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