发明名称 |
AGENT FOR INHIBITING OR IMPROVING DECREASE OF LORICRIN, TRANSGLUTAMINASE-3 ACTIVATOR, AND AGENT FOR PROMOTING FORMATION OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE OR FOR STRENGTHENING STRUCTURE OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE |
摘要 |
The present invention relates to: an agent for inhibiting or improving the decrease of loricrin in a cornified envelope of a horny cell layer of the skin, a transglutaminase-3 activator, and an agent for promoting the formation of a cornified envelope of a horny cell layer of the skin or for strengthening the structure of a cornified envelope of a horny cell layer of the skin, each of which contains sphingomyelin as an active ingredient; a composition; and a food or beverage. According to the present invention, it becomes possible to inhibit or improve the decrease of loricrin in a cornified envelope of a horny cell layer of the skin, and it also becomes possible to activate transglutaminase-3 in a cornified envelope of a horny cell layer of the skin. Therefore, it becomes possible to promote the formation of a cornified envelope of a horny cell layer of the skin and strengthen the structure of a cornified envelope of a horny cell layer of the skin. Due to these effects, the deterioration of a barrier function of skin can be prevented, inhibited or improved in a safe, simple and economically advantageous manner. |
申请公布号 |
WO2016104665(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
WO2015JP86155 |
申请日期 |
2015.12.25 |
申请人 |
MEIJI CO., LTD. |
发明人 |
OHBA, CHISATO;MORIFUJI, MASASHI;ICHIKAWA, SATOMI;KAWAHATA, KEIKO |
分类号 |
A61K31/688;A23L33/10;A61P3/02;A61P17/00;A61P17/12;A61P17/16;A61P43/00 |
主分类号 |
A61K31/688 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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