发明名称 ORAL FORMULATIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF
摘要 The present disclosure provides pharmaceutical compositions comprising cytidine analogs for oral administration, wherein the compositions release the cytidine analog substantially in the stomach. Also provided are methods of diffuse large B-cell lymphoma, follicular lymphoma, or mantel cell lymphoma, which comprises administering to a human having diffuse large B-cell lymphoma, follicular lymphoma, or mantel cell lymphoma a therapeutically effective amount of 5-azacytidine, or a pharmaceutically acceptable salt, solvate or hydrate thereof, and optionally administering therapeutically effective amounts of one or more additional active agents.
申请公布号 US2016250246(A1) 申请公布日期 2016.09.01
申请号 US201615052622 申请日期 2016.02.24
申请人 Celgene Corporation 发明人 BACKSTROM Jay T.;ETTER Jeffrey B.;LAI Mei
分类号 A61K31/7068;A61K9/48;A61K9/20;A61K45/06;A61K31/282 主分类号 A61K31/7068
代理机构 代理人
主权项
地址 Summit NJ US