发明名称 免疫刺激因子担持微粒子
摘要 PROBLEM TO BE SOLVED: To provide an immunoadjuvant that excels in biocompatibility, and can efficiently exert a strong immunostimulating activity, and that can be used to a cancer immunotherapy including a treatment of cancer or the like.SOLUTION: The immunostimulating agent support fine particle is such that tuberculin, purified tuberculin, BCG bacterium formulation, a human type Mycobacterium bovis hot-water extract, granulocyte, a macrophage colony stimulating factor or interleukin 2 is supported with calcium phosphate to the surface of fine particles including mesoporous silica, zinc-containing tricalcium phosphate of 0.5-7 mol% of a zinc content or magnesium-containing tricalcium phosphate of 0.5-7 mol% of a magnesium content as an immunostimulating agent.
申请公布号 JP5999639(B2) 申请公布日期 2016.09.28
申请号 JP20120256469 申请日期 2012.11.22
申请人 国立研究開発法人産業技術総合研究所;セルメディシン株式会社 发明人 王 秀鵬;李 霞;伊藤 敦夫;十河 友;大野 忠夫;坪井 康次;ゲレルチュルン アリウンゲレル
分类号 A61K39/39;A61K9/14;A61K39/00;A61K47/02;A61K47/04;A61P35/00 主分类号 A61K39/39
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