摘要 |
<p>The present invention relates to the treatment of B-cell lineage tumours (such as acute or chronic lymphocitic leukemias, acute or chronic myelogenous leukemias or Hodgkin's or non Hodgkin's lymphomas) using arabinofuranosyl purine (ara-G) derivatives of formula (I), wherein R1 is a C1-5 alkoscy or a pharmaceutically acceptable derivative thereof (such as compounds esterified or derivatized on the sugar residue). These compounds can also be used in combination with a second therapeutic agent such as sludarabine for the same use(s).</p> |