| 摘要 |
The present invention provides pharmaceutical compositions comprising a glucuronate salt of a piperazine compound, useful as a modulation of one or more GPCRs. In general, this salt form, and pharmaceutically acceptable compositions thereof, is useful for treating or lessening the severity of a variety of diseases or disorders including Parkinson's disease, stress/anxiety, Alzheimer's disease, Huntington's disease, panic disorders, obsessive compulsive disorder, eating disorders, drug addiction, social phobias, aggression or agitation, migraine, scleroderma and Raynaud's phenomenon, emesis, a Gl tract disorder related to the regulation of peristalsis, RLS, or prolactin secretion arising from tumours of the pituitary gland., (I) |
