SYNTHETIC OLIGOSACCHARIDES FOR P. >AERUGINOSA VACCINE.

摘要

The present invention provides synthetic >Pseudomonas aeruginosa lipooligosaccharide (LOS)-based oligosaccharides and conjugates containing various >P. aeruginosa serotype-specific oligosaccharide antigens or various core >P. aeruginosa oligosaccharide structures or motifs. The invention further provides >P. aeruginosa LOS-based immunogenic and immunoprotective compositions and antibodies derived therefrom for diagnosing, treating, and preventing infections caused by >P. aeruginosa..