SYSTEM AND METHOD FOR ANALYZING TISSUE INTRA-OPERATIVELY USING MASS SPECTROMETRY

摘要

A system and method for ample analysis including acquiring a tissue sample, preparing the tissue sample for mass spectrometry imaging, conducting a mass spectrometry procedure on the tissue sample to produce an image, analyzing the image to determine the presence or absence of a biomarker; and generating a report indicating a presence or absence of cancer.

主权项

1. A system for determining a presence of cancer in a tissue sample, the system comprising:
a sampling probe; a mass spectrometry apparatus in communication with the sampling probe and configured to receive the tissue sample and analyze the tissue sample using a mass spectrometry process to generate mass spectrometry data; a computer system including a computer processor having access to a non-transitory, computer-readable storage medium having stored thereon instructions that cause the computer processor to:
receive the mass spectrometry data from the mass spectrometry apparatus;analyze the mass spectrometry data to determine a presence of at least one potential biomarker indicating the presence of cancer in the tissue sample;access a database of at least one of biomarker information and biomarker analysis algorithms;analyze the at least one potential biomarker using the at least one of the biomarker information and biomarker analysis algorithms to determine a presence of the at least one potential biomarker in the tissue sample; anddetermine, from the presence of the at least one potential biomarker in the tissue sample, a likelihood of cancer in the tissue sample; and a report generator configured to deliver a report indicating the likelihood of cancer in the tissue sample.