发明名称 NOVEL METHODS
摘要 The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., glioblastoma and ovarian hyperstimulation syndrome. The invention provides, inter alia, methods of treating or controlling a disease condition mediated by an aquaporin, e.g., diseases or conditions of water imbalance and other diseases.
申请公布号 US2016346302(A1) 申请公布日期 2016.12.01
申请号 US201415034543 申请日期 2014.11.06
申请人 AEROMICS, INC. 发明人 PELLETIER Marc F.;MCGUIRK Paul Robert;FARR George William;WILLIAMS Steven
分类号 A61K31/661;A61K31/167 主分类号 A61K31/661
代理机构 代理人
主权项 1. A method of treating or controlling a disease or condition mediated by an aquaporin comprising administering to a patient in need thereof an effective amount of a phenylbenzamide inhibitor of aquaporin, wherein the condition to be treated or controlled is glioblastoma, ovarian hyperstimulation syndrome, pulmonary edema, fibromyalgia, or multiple sclerosis.
地址 Cleveland OH US