Multiwell plate and method for making multiwell plate using a low cytotoxicity photocurable adhesive

摘要

A multiwell plate is described herein that can be used in cell-based applications and is made from a plastic upper plate which forms the sidewalls of one or more wells and a glass lower plate which forms the bottom walls of the wells. The plastic upper plate and glass lower plate are attached and bound to one another by a cationically photocured adhesive. A preferred cationically photcured adhesive includes: (1) one or more photocationally polymerizable epoxy and/or oxetane functional resins; (2) a low fluorescing cationic photoinitiator; and (3) a low fluorescing photosensitizer if the cationic photoinitiator does not have an adequate absorption at a wavelength >280 nm to initiate cure. Also described herein is a method for making such multiwell plates.