Preparation Method of Fibrous Mats comprising PLGA/PCL Complex

摘要

PURPOSE: A manufacturing method of a fibrous mat including PLGA and PCL composite is provided to enhance biocompatibility, thereby being applicable to various systems engineering as materials. CONSTITUTION: A manufacturing method of a fibrous mat including PLGA and PCL composite comprises the following steps: manufacturing a mixture of THF(tetrahydrofuran) and PLGA(poly(lactic-co-glycolic acid)); manufacturing a mixture of MC(methyl chloride) and PCL(polycaprolactone); and manufacturing a fibrous mat by mixing and electro spinning two manufactured solutions. A mixing ratio of PCL and PLGA is 5~40:95~60d and a mixing ratio of PCL and PLGA is 10:90, 20:80 or 30:70. If a mixing ratio of PLGA and PCL is 5~15:85~95, a diameter more than 60% of the fiber which comprises the fibrous mat is about 400~600 nm, and if a mixing ratio of PLGA and PCL is 15~25:85~75, a diameter more than 60% of the fiber which comprises the fibrous mat is about 800~1200 nm.