发明名称 |
USE OF RAD18 INHIBITORS IN THE TREATMENT OF TUMORS |
摘要 |
The present invention relates to the use of an inhibitor of Rad18 expression or activity, in treating a tumor or in sensitizing a patient affected with a tumor, to a treatment with an antineoplastic agent that is a DNA damaging chemotherapeutic agent so to both reduce the self renewal of cancer stem cells and increase the DNA damage response thus boosting apoptotic cell death. |
申请公布号 |
WO2016102517(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
WO2015EP80883 |
申请日期 |
2015.12.21 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
MAIORANO, DOMENICO |
分类号 |
C07K16/18;A61K31/00;C12N15/11;C12N15/113 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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