发明名称 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF
摘要 Described herein are synthetic, modified RNAs for changing the phenotype of a cell, such as expressing a polypeptide or altering the developmental potential. Accordingly, provided herein are compositions, methods, and kits comprising synthetic, modified RNAs for changing the phenotype of a cell or cells. These methods, compositions, and kits comprising synthetic, modified RNAs can be used either to express a desired protein in a cell or tissue, or to change the differentiated phenotype of a cell to that of another, desired cell type.
申请公布号 EP3072961(A1) 申请公布日期 2016.09.28
申请号 EP20160151377 申请日期 2011.04.15
申请人 CHILDREN'S MEDICAL CENTER CORPORATION 发明人 ROSSI, DERRICK;WARREN, LUIGI
分类号 C12N5/10;C07H21/00;C12N5/074;C12N15/113 主分类号 C12N5/10
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