METHOD AND APPARATUS FOR DELIVERY OF SUBMICROLITER VOLUMES ONTO A SUBSTRATE

摘要

A slotted pin tool, a delivery system containing the pin tool, a substrate f or use I the system and methods using the pin tool and system are provided. The slotted pin tool contains a plurality of pins having slotted ends designed t o fit around each loci of material deposited on a surface, such as a microarra y, without contacting any of the deposited material. Sample is delivered by contacting the pin tool with the surface; the amount delivered is proportion al to the velocity of the pin tool as it contacts the surface or the velocity o f the liquid when movement of the pin is halted.