CYCLODEXTRIN-CONTAINING PHARMACEUTICAL PREPARATION

摘要

A water-based preparation or aqueous solution which is a transparent aqueous solution containing a cyclodextrin and a sufficient amount of ebselen and usable as an injection; an injection comprising the aqueous solution; a dripping preparation comprising the aqueous solution; a process for producing an aqueous solution of ebselen and a cyclodextrin which comprises dissolving ebselen in a water-miscible organic solvent, separately dissolving a cyclodextrin in an aqueous medium, mixing the two solutions, subsequently drying the mixture, and mixing the resultant dried mixture with an aqueous medium; a dry pharmaceutical preparation which comprises ebselen and a cyclodextrin; and a process for producing a solution of ebselen and a cyclodextrin which comprises dissolving ebselen in a water-miscible organic solvent, separately dissolving a cyclodextrin in an aqueous medium, and then mixing the two solutions.