| 摘要 |
<p>The present invention relates to a spacer 16, such as a polymeric spacer, for use with an implant device 12, e.g., a bone plate, for splinting a fracture of a bone 14. The spacer 16 includes a body 26 defining a bone healing surface 34, wherein at least a portion of the bone healing surface 34 has a coating 18 which includes a therapeutic agent, a polymeric carrier, and a buffer medium to stimulate bone growth and/or promote fracture healing. A kit is also disclosed which includes one or more of the spacers 16, at least one bone plate 12, and optionally one or more bone screws 24 for securing the bone plate 12 to bone 14. A method for promoting fracture healing in bone 14 is further disclosed which includes securely situating a coated portion of the spacer 16 adjacent bone 14.</p> |
