发明名称 |
Sinomenine Derivatives and Preparation and Uses Thereof |
摘要 |
The present invention relates to the preparation and pharmacological use of sinomenine derivatives of formula I. The approach disclosed herein is the modification of D ring by-substituting for R. Additional substitutions in the other rings are also provided herein. Several of the sinomenine derivatives have significantly greater anti-inflammation activity when compared with the parent compound.
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申请公布号 |
US2008318966(A1) |
申请公布日期 |
2008.12.25 |
申请号 |
US20060096543 |
申请日期 |
2006.12.15 |
申请人 |
WANG JIE;PAN YI |
发明人 |
WANG JIE;PAN YI |
分类号 |
A61K31/439;A61K31/4985;C07D221/22;C07D471/08;C12N5/00 |
主分类号 |
A61K31/439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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