发明名称 COMBINATION OF ANTI-CTLA4 ANTIBODY WITH DIVERSE THERAPEUTIC REGIMENS FOR THE SYNERGISTIC TREATMENT OF PROLIFERATIVE DISEASES
摘要 A method for the treatment of cancer, comprising the administration to a mammal in need thereof a synergistic, therapeutically effective amount of (i) an anti-CTLA-4 antibody, in addition to one or more diluents, vehicles, excipients, and/or inactive ingredients, and (ii) N (2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1 -piperazinyl]-2-methyl-4pyrimidinyl] amino] -5-thiazolecarboxamide (dasatinib), or a pharmaceutically acceptable salt, solvate, or hydrate thereof, in addition to one or more diluents, vehicles, excipients, and/or inactive ingredients.
申请公布号 AU2015203324(B2) 申请公布日期 2016.07.28
申请号 AU20150203324 申请日期 2015.06.17
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 LEE, FRANCIS Y.;JURE-KUNKEL, MARIA
分类号 C07K16/28;A61K31/337;A61K31/385;A61K31/506;A61K33/24;A61K39/395;A61K45/06;A61P35/00;C07K16/18 主分类号 C07K16/28
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