Provided are Conjugate of formula l L-(LU-D)p (I) wherein L is a ligand unit, LV is a linker unit and D is a drug unit comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
申请公布号
CA2795349(C)
申请公布日期
2016.11.29
申请号
CA20112795349
申请日期
2011.04.15
申请人
SEATTLE GENETICS, INC.;SPIROGEN DEVELOPMENTS SARL
发明人
HOWARD, PHILIP WILSON;JEFFREY, SCOTT;BURKE, PATRICK;SENTER, PETER
