发明名称 CEST SYSTEMS PROVIDING SENSITIVITY NOT DEPENDING ON CONCENTRATION
摘要 FIELD: medicine.SUBSTANCE: group of inventions relates to medicine, particularly to use of non-equvalent mobile protons, relating to different NMR stereoisomers of CEST-agent, in ratiometric imaging method using CEST and to complex lanthanide compounds (III), having at least two distinguishable by NMR stereoisomers in solution used as sensitive CEST-agents not depending on concentration.EFFECT: distinguished by NMR stereoisomers of CEST-agent are applied as useful biomarkers of certain disease, preciously associated with these changes.13 cl, 21 dwg, 10 ex
申请公布号 RU2605823(C2) 申请公布日期 2016.12.27
申请号 RU20130125778 申请日期 2011.11.04
申请人 BRAKKO IMEDZHING SpA 发明人 AJME, Silvio;TERRENO, Entso;DELLI KASTELLI, Daniela;LONGO, Dario Livio;FEDELI, Franko;UGGERI, Fulvio
分类号 A61K49/10;G01R33/48 主分类号 A61K49/10
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