| 发明名称 |
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE LECT2 GENE |
| 摘要 |
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LECT2 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of LECT2. |
| 申请公布号 |
US2016264966(A1) |
申请公布日期 |
2016.09.15 |
| 申请号 |
US201415026897 |
申请日期 |
2014.10.01 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
Fitzgerald Kevin;Sehgal Alfica;Bettencourt Brian;Hinkle Gregory |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A double-stranded ribonucleic acid (dsRNA) for inhibiting expression of LECT2, wherein said dsRNA comprises a sense strand that is 15-30 base pairs in length and an antisense strand that is 15-30 base pairs in length and the antisense strand is complementary to at least 15 contiguous nucleotides of SEQ ID NO: 1. |
| 地址 |
Cambridge MA US |
