| 发明名称 |
MODULATOR OF ATP-BINDING CASSETTE TRANSPORTER |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide modulators of ATP-binding cassette ('ABC') transporters or their fragments. <P>SOLUTION: The modulators, which include cystic fibrosis transmembrane conductance regulator, of the ATP-binding cassette ('ABC') transporters or their fragments are provided. A composition for the modulators, and a method using the modulators are also provided. Methods of treating ABC transporter mediated diseases using the modulators are also provided. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012056963(A) |
申请公布日期 |
2012.03.22 |
| 申请号 |
JP20110266327 |
申请日期 |
2011.12.05 |
| 申请人 |
VERTEX PHARMACEUTICALS INC |
发明人 |
HADIDA RUAH SARAH S;HAZLEWOOD ANNA R;GROOTENHUIS PETER D J;VAN GOOR FREDRICK F;SINGH ASHVANI K;ZHOU JINGLAN;MCCARTNEY JASON |
| 分类号 |
C07D215/56;A61K31/47;A61K31/4709;A61K31/496;A61K31/498;A61K31/506;A61K31/5377;A61K31/5415;A61K31/55;A61P3/06;A61P3/10;A61P5/00;A61P7/00;A61P7/04;A61P7/12;A61P11/00;A61P17/00;A61P19/08;A61P21/00;A61P21/04;A61P25/14;A61P25/16;A61P25/28;A61P27/04;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D471/04;C07D471/10 |
主分类号 |
C07D215/56 |
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