CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION
摘要
The present invention relates to 1-(cyclohexyloxycarbonyloxy)ethyl 1-((2'-cyanobiphenyl-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate in crystalline form and a process for its preparation, which is useful intermediate in the preparation of candesartan cilexetil. The present invention also relates to the preparation of candesartan cilexetil and pharmaceutical composition comprising candesartan cilexetil.
申请公布号
WO2008129077(A3)
申请公布日期
2009.01.29
申请号
WO2008EP54997
申请日期
2008.04.24
申请人
KRKA, D.D. NOVO MESTO;ZUPANCIC, SILVO;SMRKOLJ, MATEJ;OSOLNIK, RENATA;VRBINC, MIHA