发明名称 CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION
摘要 The present invention relates to 1-(cyclohexyloxycarbonyloxy)ethyl 1-((2'-cyanobiphenyl-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate in crystalline form and a process for its preparation, which is useful intermediate in the preparation of candesartan cilexetil. The present invention also relates to the preparation of candesartan cilexetil and pharmaceutical composition comprising candesartan cilexetil.
申请公布号 WO2008129077(A3) 申请公布日期 2009.01.29
申请号 WO2008EP54997 申请日期 2008.04.24
申请人 KRKA, D.D. NOVO MESTO;ZUPANCIC, SILVO;SMRKOLJ, MATEJ;OSOLNIK, RENATA;VRBINC, MIHA 发明人 ZUPANCIC, SILVO;SMRKOLJ, MATEJ;OSOLNIK, RENATA;VRBINC, MIHA
分类号 C07D235/26;A61K31/4184;A61P9/00 主分类号 C07D235/26
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