发明名称 |
BIOMARKER FOR ALZHEIMER'S DISEASE OR MILD COGNITIVE IMPAIRMENT |
摘要 |
Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used. |
申请公布号 |
EP2631646(B1) |
申请公布日期 |
2016.10.19 |
申请号 |
EP20110834097 |
申请日期 |
2011.06.23 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
SATO, YOSHIAKI;AOSHIMA, KEN;BERNIER, FRANCOIS |
分类号 |
G01N33/50;G01N33/15;G01N33/68;G01N33/92 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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