发明名称 A crystalline anhydrous form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof
摘要 The present invention relates to a new anhydrous crystalline form of Cabazitaxel of formula (I), designated as form H. A further object of the present invention is a processes for the preparation of the above mentioned form H by recrystallization of Cabazitaxel from a mixture of decanoyl- and octanoyl triglycerides or from glycerol trioctanoate. Form H of Cabazitaxel is useful for the preparation of Cabazitaxel, Cabazitaxel salts, and polymorphic forms thereof. It is also particularly useful as a medicament, especially for the treatment of cancers.
申请公布号 IL245260(D0) 申请公布日期 2016.06.30
申请号 IL20160245260 申请日期 2016.04.21
申请人 INDENA S.P.A. 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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