| 发明名称 | Treatment of squamous cell carcinoma with HSP27 antisense oligonucleotides and radiotherapy | ||
| 摘要 | Squamous cell carcinomas, such as squamous head and neck cancer, are treated with a combination of radio-therapy and a therapeutic agent that reduces the amount of hsp27 in the squamous cancer cells. In specific embodiments, the therapeutic agent that reduces the amount of hsp27 is an antisense oligonucleotide therapeutic agent. | ||
| 申请公布号 | US9381209(B2) | 申请公布日期 | 2016.07.05 |
| 申请号 | US200812528118 | 申请日期 | 2008.03.04 |
| 申请人 | The University of British Columbia | 发明人 | Rodriguez-Lafrasse Claire;Hadchity Elie |
| 分类号 | A61K48/00;A61K31/712;A01K67/027;A61K31/7088;A61K31/7125 | 主分类号 | A61K48/00 |
| 代理机构 | Larson & Anderson, LLC | 代理人 | Larson & Anderson, LLC |
| 主权项 | 1. A method for treatment of squamous cell carcinoma characterized by elevated expression of hsp27 as compared to non-cancerous cells of the same type in an individual suffering from the cancer, comprising treating a patient diagnosed with a squamous cell carcinoma with a combination of radio-therapy and a therapeutic agent that reduces the amount of hsp27 in the squamous cancer cells, wherein the therapeutic agent that reduces the amount of hsp27 is an antisense oligonucleotide therapeutic. | ||
| 地址 | Vancouver CA | ||