Ingredients for inhalation and methods for making the same

摘要

A method of processing an active ingredient, the method comprising submitting a pharmaceutically active ingredient in the absence of excipients and/or additives to compression and shearing forces. The invention also relates to compositions comprising an active prepared by the method.

主权项

1. A method of processing an active ingredient, the method consisting of feeding a pharmaceutically active ingredient to a mechanofusion apparatus and subjecting the pharmaceutically active ingredient to compression and shearing forces, wherein the active ingredient is micronized prior to compression and shearing forces and wherein the active ingredient is glycopyrrolate.