Methods of inducing sedation

摘要

The present invention provides methods of inducing sedation in a subject by administering an effective amount of a compound or a mixture of compounds according to Formula I. Compounds of Formula I are a class of halogenated alcohol derivatives with a vapor pressure of less than 0.1 atmospheres (76 mmHg) at 25° C. The compounds of the present invention can be administered by any route sufficient to achieve a desired anesthetic, amnestic, analgesic, or sedative effect.

主权项

1. A method of inducing sedation in a subject, comprising administering to the subject via the respiratory system an effective amount of a compound or a mixture of compounds of Formula I: wherein: n is 0-4, R1 is H; R2, R3, R4, R5 and R6 independently are selected from H, X, CX3, CHX2, CH2X and C2X5; and wherein X is a fluorine, the administered compound having a vapor pressure of less than 0.1 atmospheres (76 mmHg) at 25° C., and the number of hydrogen atoms in Formula I do not exceed the number of carbon atoms, thereby inducing sedation in the subject.