| 发明名称 | Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals | ||
| 摘要 | The present invention relates to pharmaceutical compositions comprising polyfunctional metal phenolates that have biological applications as an anticancer adjuvant, cytoprotective antimetastatic agents and antimutagenic agents when associated with chemotherapy drugs.;The present invention further relates to the use of said polyfunctional metal phenolates in the preparation of drugs for the treatment, prophylaxis or prevention of neoplasic diseases in humans and animals. | ||
| 申请公布号 | US9381169(B2) | 申请公布日期 | 2016.07.05 |
| 申请号 | US200913377194 | 申请日期 | 2009.11.11 |
| 申请人 | UNIVERSIDADE BANDEIRANTE DE SÃO PAULO—ACADEMIA PAULISTA ANCHIETA S/C LT;FUNDAÇ ÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO—FAPESP | 发明人 | Quincoces Suárez José Agustin;Maria Durvanei Augusto;Pardi Paulo Celso;Flores Fernanda Faião;Pereira Santos Reginaldo;Gonçales Rando Daniela |
| 分类号 | A61K31/121;A61K31/337;A61P35/00;A61P35/04;A61K31/375;A61K31/675;A61K31/7048;A61K45/06 | 主分类号 | A61K31/121 |
| 代理机构 | Nixon Peabody LLP | 代理人 | Resnick David S.;Nixon Peabody LLP |
| 主权项 | 1. A pharmaceutical composition comprising sodium 4-[5-(4-hydroxy-3-methoxy-phenyl)-3-oxo-penta-1,4-dienil]-2-methoxy-phenolate and paclitaxel, wherein paclitaxel and sodium 4-[5-(4-hydroxy-3-methoxy-phenyl)-3-oxo-penta-1,4-dienil]-2-methoxy-phenolate are in molar ratio from 15,000:1.6 to 15,000:0.83. | ||
| 地址 | São Paulo BR | ||