发明名称 |
CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION |
摘要 |
Provided are methods of using curcuphenol compounds to increase expression of major histocompatibility complex class I (MHC-I) antigen in cells, particularly on the surface of diseased cells such as cancer cells, and thereby increase the immunogenicity of the cells. Also provided are pharmaceutical compositions that comprise curcuphenol compounds and methods of use thereof, for instance, to treat various cancers, alone or in combination with other therapies. |
申请公布号 |
EP3071192(A1) |
申请公布日期 |
2016.09.28 |
申请号 |
EP20140815145 |
申请日期 |
2014.11.20 |
申请人 |
BIOMMUNE TECHNOLOGIES INC. |
发明人 |
JEFFERIES, WILFRED A;GABATHULER, REINHARD;ANDERSEN, RAYMOND;WILLIAMS, DAVID;NOHARA, LILIAN |
分类号 |
A61K31/05;A61K31/12;A61K45/06;A61P35/00 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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