发明名称 |
Verfahren zur Auffindung von medizinisch wertvollen Wirkstoffen |
摘要 |
The invention relates to a method for identifying inhibitors or ligands for binding domains. The inventive method comprises using a protein that has at least one catalytic domain, incubating it with a marker substrate that binds to the catalytic domain of the protein and reacts therewith, with a substrate that can reversibly bind to the catalytic domain and to the binding domain, and with the inhibitor, and detecting whether the protein reacts with the marker substrate.
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申请公布号 |
DE10028204(A1) |
申请公布日期 |
2002.01.03 |
申请号 |
DE20001028204 |
申请日期 |
2000.06.09 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
WEITHMANN, KLAUS-ULRICH |
分类号 |
A61K31/44;A61K31/702;A61K38/00;A61P1/02;A61P1/04;A61P1/14;A61P9/10;A61P17/02;A61P19/02;A61P25/00;A61P25/04;A61P27/00;A61P29/00;A61P31/04;A61P35/00;A61P35/04;A61P37/02;A61P43/00;C07D211/70;C12Q1/37;(IPC1-7):C07D211/70;A61K31/452 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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