发明名称 Taxol enhancer compounds.
摘要 There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein Y, Z and R 1 to R 6 have meanings given in the description, for use in the treatment of melanoma or renal cancer by administration of said compound, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog. There is also provided the use of a compound of formula (I) for the production of a medicament for administration, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog, for treating melanoma or renal cancer.
申请公布号 ZA200401051(B) 申请公布日期 2005.06.22
申请号 ZA20040001051 申请日期 2004.02.09
申请人 SYNTA PHARMACEUTICALS CORP. 发明人 KEIZO KOYA;SHOUJUN CHEN;YAMING WU;LIJUN SUN;NORIAKI TATSUTA;MISUNORI ONO
分类号 C07D213/77;A45D8/00;A45D8/12;A45D8/20;A45D8/36;A61K;A61K31/16;A61K31/197;A61K31/337;A61K31/34;A61K31/4035;A61K31/444;A61K31/5355;A61P;A61P35/00;C07C;C07C327/00;C07C327/56;C07D209/42;C07D209/44;C07D213/83;C07D261/18;C07D307/68;C07D333/38;C07D333/68 主分类号 C07D213/77
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