发明名称 |
DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE |
摘要 |
The present invention provides methods of inducing differentiation of oligodendrocyte progenitor cells to a mature myelinating cell fate with a neurotransmitter receptor modulating agent. The present invention also provides methods of stimulating increased myelination in a subject in need thereof by administering said neurotransmitter receptor modulating agent. Methods of treating a subject having a demyelinating disease using a neurotransmitter receptor modulating agent are also provided. |
申请公布号 |
US2016166687(A1) |
申请公布日期 |
2016.06.16 |
申请号 |
US201514973105 |
申请日期 |
2015.12.17 |
申请人 |
The Scripps Research Institute ;IRM LLC |
发明人 |
Schultz Peter;Lairson Luke;Deshmukh Vishal;Lyssiotis Costas |
分类号 |
A61K39/395;A61K31/135;A61K38/21;A61K31/5415;A61K31/137;A61K31/439;A61K31/40 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
La Jolla CA US |