发明名称 Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries
摘要 A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
申请公布号 US8175702(B2) 申请公布日期 2012.05.08
申请号 US20050266755 申请日期 2005.11.03
申请人 EFIMOV IGOR R.;KRINSKI VALENTIN I.;NIKOLSKI VLADIMIR P.;THE WASHINGTON UNIVERSITY 发明人 EFIMOV IGOR R.;KRINSKI VALENTIN I.;NIKOLSKI VLADIMIR P.
分类号 A61N1/00 主分类号 A61N1/00
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