发明名称 |
SUBSTITUTED N-PHENYL-PYRROLIDINYLMETHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF AS HISTAMINE H3 RECEPTOR MODULATORS |
摘要 |
<p>The present invention discloses and claims a series of substituted N-phenyl-pyrrolidinylmethylpyrrolidine amides of formula (I) as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, this invention also discloses methods of preparation of substituted pyrrolidinylmethylpyrrolidine amides and intermediates therefor.</p> |
申请公布号 |
WO2009052063(A1) |
申请公布日期 |
2009.04.23 |
申请号 |
WO2008US79758 |
申请日期 |
2008.10.14 |
申请人 |
SANOFI-AVENTIS;CZECHTIZKY, WERNGARD;GAO, ZHONGLI;HURST, WILLIAM J.;SCHWINK, LOTHAR;STENGELIN, SIEGFRIED |
发明人 |
CZECHTIZKY, WERNGARD;GAO, ZHONGLI;HURST, WILLIAM J.;SCHWINK, LOTHAR;STENGELIN, SIEGFRIED |
分类号 |
C07D207/09;A61K31/4025;A61P25/00;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D413/12;C07D471/04 |
主分类号 |
C07D207/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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