发明名称 PROCESS FOR THE PREPARATION OF EFINACONAZOLE
摘要 The present invention provides an improved process for the preparation of Efinaconazole in higher yield by the ring-opening addition reaction of epoxytriazole with 4- methylenepiperidine or its acid addition salt under mild conditions without using a large 5 excess of 4-methylenepiperidine in the presence of an alkali or an alkaline earth metal halide.
申请公布号 WO2016181306(A1) 申请公布日期 2016.11.17
申请号 WO2016IB52667 申请日期 2016.05.10
申请人 LUPIN LIMITED 发明人 SASANE, Sachin, Arun;VARMA, Devendrakumar, Paramsukh;VYAS, Rajesh, Harishankar;BHISE, Nandu, Baban;SINGH, Girij, Pal;KUMBHAR, Krishnat, Hanmant
分类号 C07D401/06 主分类号 C07D401/06
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