摘要 |
PROBLEM TO BE SOLVED: To provide an amino alcohol or its pharmacologically acceptable salt that has excellent immunosuppressant action. SOLUTION: The amino alcohol is represented by general formula (I) (wherein R<SP>1</SP>and R<SP>2</SP>are each H or a lower alkyl; R<SP>3</SP>is a lower alkyl; n is 2 or 3; X is a S atom or an N atom which may be substituted with a lower alkyl; Y is a group bearing a structure represented by the formula: -C(=O)-CH<SB>2</SB>-; Z is an ethylene or the like; R<SP>4</SP>is an aryl or a substituted aryl; R<SP>5</SP>is H, a halogen atom or a low alkyl wherein when R<SP>1</SP>and R<SP>2</SP>are each H, R<SP>5</SP>is a halogen atom or a low alkyl). COPYRIGHT: (C)2005,JPO&NCIPI |