发明名称 |
SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA-SECRETASE-INHIBITING ACTIVITY |
摘要 |
Disclosed are beta amyloid inhibiting compounds of formulae (I), (II), (III) and (IV) or their pharmaceutically acceptable salts or solvates thereof useful in treating Alzheimer's disease, wherein the substituents are as described within the specification. Further disclosed is a pharmaceutical composition comprising a compound of formulae (I), (II), (III) or (IV), and the use of said compounds in the manufacture of a medicament for inhibiting beta secretase activity. |
申请公布号 |
NZ589590(A) |
申请公布日期 |
2012.05.25 |
申请号 |
NZ20090589590 |
申请日期 |
2009.06.11 |
申请人 |
SHIONOGI & CO., LTD |
发明人 |
HORI, AKIHIRO;FUJIKOSHI, CHIAKI;MATSUMOTO, SAE;KOORIYAMA, YUUJI;UENO, TATSUHIKO;KATO, TERUKAZU;YONEZAWA, SHIJU |
分类号 |
C07D417/12;A61K31/4439;A61K31/497;A61K31/541;A61P25/28;A61P43/00;C07D417/10;C07D417/14 |
主分类号 |
C07D417/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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