发明名称 |
Polarization-enhanced detector with gold nanorods for detecting nanoscale rotational motion and method therefor |
摘要 |
A nanoscale motion detector attaches a gold nanorod (30) to the rotating arm (26) of a molecular structure (10) to cause the nanoparticle to rotate. The molecular structure is an F1-ATPase enzyme. The gold nanorod is exposed to a light source. The long axis of the gold nanorod scatters red light when the nanorod is in a first position. The short axis of the gold nanorod scatters green light when the nanorod is in a second position. A polarizing filter filters the red and green light to detect the rotational motion by observing alternating red and green lights. A detection DNA stand (50) is coupled between the gold nanorod and the molecular structure. The detection DNA strand hybridizes with a target DNA strand (58) if the target DNA strand matches the detection DNA strand to form a structural link between the molecular structure and gold nanorod.
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申请公布号 |
US8192936(B2) |
申请公布日期 |
2012.06.05 |
申请号 |
US201113103407 |
申请日期 |
2011.05.09 |
申请人 |
FRASCH WAYNE D.;CHAPSKY LARS;ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY |
发明人 |
FRASCH WAYNE D.;CHAPSKY LARS |
分类号 |
C12Q1/68;C07H21/04;G01P3/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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