发明名称 Polarization-enhanced detector with gold nanorods for detecting nanoscale rotational motion and method therefor
摘要 A nanoscale motion detector attaches a gold nanorod (30) to the rotating arm (26) of a molecular structure (10) to cause the nanoparticle to rotate. The molecular structure is an F1-ATPase enzyme. The gold nanorod is exposed to a light source. The long axis of the gold nanorod scatters red light when the nanorod is in a first position. The short axis of the gold nanorod scatters green light when the nanorod is in a second position. A polarizing filter filters the red and green light to detect the rotational motion by observing alternating red and green lights. A detection DNA stand (50) is coupled between the gold nanorod and the molecular structure. The detection DNA strand hybridizes with a target DNA strand (58) if the target DNA strand matches the detection DNA strand to form a structural link between the molecular structure and gold nanorod.
申请公布号 US8192936(B2) 申请公布日期 2012.06.05
申请号 US201113103407 申请日期 2011.05.09
申请人 FRASCH WAYNE D.;CHAPSKY LARS;ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY 发明人 FRASCH WAYNE D.;CHAPSKY LARS
分类号 C12Q1/68;C07H21/04;G01P3/68 主分类号 C12Q1/68
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